Reflux Nephropathy is the condition of kidney damage due to the backward flow of urine from bladder into kidneys. The disease is more common in children and causes inveterate childhood abnormality in urinary tract and the long term disease is alleged to cause chronic pyelonephritis, high blood pressure, excessive protein loss, obstructive uropathy and kidney failure. Reflux Nephropathy is supposed to occur in people whose ureters are not attached properly to the bladder, when the valves are not working well or at the time of kidney transplant followed by the swelling of ureters. The treatment of Reflux Nephropathy includes surveillance, medical therapy and surgical therapy which is distributed among 5 different grades depending upon the gravity of reflux. The treatment of reflux nephropathy aims to reduce the renal scarring and kidney infections by usage of Prophylactic Antibiotics, antihypertensive medications, pain medications, urine culture and yearly ultrasound of the kidneys. The severe reflux nephropathy require surgery when the medical therapy fails to respond. In few cases, surgery includes ureteral re-implantation to stop the backward flow of urine. The treatment of the reflux nephropathy depends on the gender and age of the patient. The medical therapy is the safest treatment among all the diagnostic treatments as the surgical approach may face some unavoidable complications.
Reflux Nephropathy is a congenital disease which causes an increase in the number of people suffering from the disease. Advancement in medication and surgical therapies, follow up care and imaging techniques impact the overall treatment market.
The emerging research and development by various academic and research institutes as well as bio-pharmaceutical companies contributes to the opening of novel treatment approaches participating in increasing the overall global market. Several awareness programs organized by government and health care sector has also led to an upsurge in the market. The drugs like antibacterial pyelonephritis and antibody trimethoprim-sulfamethoxazole are effective antibiotic to prevent the infections but the scarcity of the drugs and threat to the patients in the surgical treatment of reflux nephropathy turns to be the limiting factor for the growth of market.
Continuous research in the area and novel product launches would provide edge to the bio pharmaceutical companies involved in the competition landscape. The research and development in the diagnostic methodology has also accelerated the progress of market. The medical therapy is the most preferred treatment method that contributes to a major part of the total market of reflux nephropathy treatment. Availability of generic medications in the market also have an impact in the overall growth of Nephropathy treatment market.
Geographically, the reflux nephropathy treatment market has been segmented into five key regions: North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. North America dominates the market because of the availability of large number of service providers and good reimbursement scenario for the treatment. This is followed by the Europe as studies demonstrates, children in these regions are 10 times more susceptible to the disease. Moreover, the health facilities and healthy reimbursement scenario is also at pinnacle in these regions. The market in Asia Pacific and Middle Eastern countries is considered to be the growing segments due to the continuous increasing number of service providers and improvement in healthcare facilities. The awareness programs conducted by the health organizations also assists the overall growth of the market in these regions.
Some major key players of the reflux nephropathy treatment market are Abbott India Ltd., Glaxo SmithKline Pharmaceutical Ltd, Cubit Healthcare, Cobalt Laboratories Inc, Actavis Mid Atlantic LLC, Aurobindo Pharma – Milpharm Ltd.
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